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Increased Time From Neoadjuvant Chemoradiation to Surgery Is Associated With Higher Pathologic Complete Response Rates in Esophageal Cancer

Saturday, January 10, 2015

Submitted by

Mark Ferguson

Source

Source Name: Annals of Thoracic Surgery

Source URL: http://www.annalsthoracicsurgery.org/article/S0003-4975%2814%2901734-2/abstract

Author(s)

Talha Shaikh, Karen Ruth, Walter J. Scott, Barbara A. Burtness, Steven J. Cohen, Andre A. Konski, Harry S. Cooper, Igor Astsaturov, Joshua E. Meyer

The authors retrospectively analyzed pathologic response rates and their relation to the interval between completion of induction therapy and esophagectomy for esophageal cancer in 88 patients. Complete response rates increased from 12.5% to 40.9% among quartiles as the interval increased from <45 days to >63 days. There was no increase in morbidity associated with longer intervals to surgery.