Of 1,579 patients undergoing esophagectomy for esophageal cancer, 60 patients underwent up-front surgery for cT2 N0 M0 esophageal cancer, of whom 8 (13 percent) were found to have pathologic T2 N0 M0, 16 (27 percent) were pathologically downstaged, and 36 (60 percent) were upstaged, 7 (19 percent) on the basis of pathologic T stage, 14 (39 percent) o
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Esophagus - Cancer
June 13, 2024
This editorial summarizes the landscape that led to the founding of the Thoracic Surgical Oncology Group in 2017, in an era when, due to various oncology group reorganizations, a need developed for a focused committee to conduct thoracic surgery oncology-based clinical trials. The group has expanded over the years to include 32 hospitals.
April 13, 2023
This study aimed to measure the quality of life (QOL) as reported by patients after esophagectomy, a procedure which has a high rate of mortality.
February 9, 2023
To understand the shift toward nonsurgical management of esophageal cancer, researchers set out to determine the long-term quality of life (QOL) after esophagectomy. This study found that, in esophagectomy patients surviving more than three years, QOL did not differ significantly from the normative population reference values.
August 12, 2021
Although the standard of care in the West for regionally advanced esophageal cancer entails induction therapy, this is routinely not the case in China. This randomized trial involving over 450 randomized participants to induction therapy (vinorelbine, cisplatin, 40 Gy RT) followed by resection vs resection alone.
June 25, 2021
Data from the Esodata project used more than 8,000 patients undergoing esophagectomy for cancer to develop a risk prediction score for 90-day mortality. Development and validation groups were used. There were 10 variables that emerged as significant predictors, and weighted values were developed into the model. The model identified 5 risk levels f
June 10, 2021
Chyle leak remains a challenging postoperative complication to manage, and avoidance is always easier than mitigation. The only predisposing factor identified in this study was low BMI. Although ICU stay was longer in affected patients, operative mortality, hospital LOS, and survival were not negatively impacted by the presence of a leak.
June 27, 2020
The previous randomized study of minimally invasive esophagectomy vs open esophagectomy (TIME trial) conducted in the Netherlands demonstrated reduced pulmonary complications and LOS with MIE. Compared to the benefits of MIE in those selected high volume centers, national use of MIE was associated with increased overall complications, increased pulm
November 26, 2019
A deep-learning computer aided detection (CAD) system was trained to recognize neoplasia using nearly 500,000 endoscopic images. In head-to-head testing against experienced gastroenterologists using additional images, the accuracy of CAD in diagnosing neoplasia was 88% vs 73% for the gastroenterologists.
October 24, 2019
The National Cancer Database was queried regarding esophageal squamous cancer cases from 2004-2013, and over 11,000 patients were identified. Definitive chemoradiotherapy was used in 79%, whereas resection was employed in 21% at some phase of therapy.