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Intensive Care in Patients with Lung Cancer: A Multinational Study

Sunday, June 22, 2014

Submitted by

Mark Ferguson

Source

Source Name: Annals of Oncology

Source URL: http://annonc.oxfordjournals.org/content/early/2014/06/20/annonc.mdu234.abstract…

Author(s)

M. Soares, A-C Toffart, J-F Timsit, G. Burghi, C. Irrazábal, N. Pattison, E. Tobar, B. F. C. Almeida, U. V. A. Silva, L. C. P. Azevedo, A. Rabbat, C. Lamer, A. Parrot, V. C. Souza-Dantas, F. Wallet, F. Blot, G. Bourdin, C. Piras, J. Delemazure, M. Durand, D. Tejera, J. I. F. Salluh, and E. Azoulay for the Lung Cancer in Critical Care (LUCCA) Study Investigators

This multicenter prospective study evaluated indications for and outcomes of ICU admission for 449 patients with lung cancer. Most patients had a newly diagnosed lung cancer, and the most common indication for ICU admission was airway compromise. Hospital and 6-month mortality rates were 39% and 55%. Determinants of mortality were severity of organ system dysfunction, recurrent or progressive cancer, poor performance status, and cancer-related complications. Mortality was lower in high volume centers.