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Liberal or Restrictive Transfusion after Cardiac Surgery

Saturday, April 4, 2015

Submitted by

Tom C. Nguyen

Source

Source Name: New England Journal of Medicine

Source URL: http://www.nejm.org/doi/full/10.1056/NEJMoa1403612

Author(s)

Gavin J. Murphy, F.R.C.S., Katie Pike, M.Sc., Chris A. Rogers, Ph.D., Sarah Wordsworth, Ph.D., Elizabeth A. Stokes, M.Sc., Gianni D. Angelini, F.R.C.S., and Barnaby C. Reeves, D.Phil. for the TITRe2 Investigators

This multicenter randomized trial examined restrictive versus liberal threshold in red-cell transfusion in patients after cardiac surgery. The results were provocative, with more deaths in the restrictiv group compared to the liberal transfusion group. Posoperative complications were also slightly higher in the restrictive group.