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Outcome of surgery versus radiotherapy after induction treatment in patients with N2 disease: systematic review and meta-analysis of randomised trials

Tuesday, July 14, 2015

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Source

Source Name: Thorax

Author(s)

PJ McElnay, A Choong, E Jordan, F Song, E Lim

This meta-analysis evaluated results from 6 studies totalling 868 patients randomized to local control (radiotherapy vs surgery) after induction therapy for NSCLC with N2 disease.  Four studies evaluated induction chemotherapy, the other 2 evaluated induction chemoradiotherapy.  Differences in outcomes were not significant, but there was a strong trend favoring surgery as part of multimodality therapy for NSCLC with N2 disease.

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