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Treatment Trends, Risk of Lymph Node Metastasis, and Outcomes for Localized Esophageal Cancer

Sunday, August 31, 2014

Submitted by

Marcelo Jimenez

Source

Source Name: Journal of the National Cancer Institute

Source URL: http://jnci.oxfordjournals.org/content/106/7/dju133.abstract

Author(s)

Ryan P. Merkow, Karl Y. Bilimoria, Rajesh N. Keswani, Jeanette Chung, Karen L. Sherman, Lawrence M. Knab, Mitchell C. Posner and David J. Bentrem

In this retrospective study based on a database of 5390 patients with early-stage esophageal cancer, T1a and T1b lesions were treated by endoscopic (26.5%) or surgical resection (73.5%). For patients undergoing surgery, the incidence of lymph node metastasis was 5.0% for T1a and 16.6% for T1b lesions. Size > 2 cm and intermediate-/high-grade lesions were the best predictors of nodal involvement. The risk of nodal metastases should be considered when counseling patients.