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Journal and News Scan

Source: The Lancet
Author(s): Zhengming Chen, Richard Peto, Maigeng Zhou, Andri Iona, Margaret Smith, Ling Yang, Yu Guo, Yiping Chen, Zheng Bian, Garry Lancaster, Paul Sherliker, Shutao Pang, Hao Wang, Hua Su,, Ming Wu, Xianping Wu, Junshi Chen, Rory Collins, Liming Li, for the China Kadoorie Biobank (CKB) collaborative group

Chinese men smoke one-third of the world's cigarettes; two-thirds of adult Chinese men are smokers.  In contrast, the percentage of women smokers is low and is decreasing (<3%).  It is estimated that by 2030 2 million annual deaths in China will be attributable to smoking.

Source: Annals of Thoracic Surgery
Author(s): Thomas L. Gentles, A. Kirsten Finucane, Bo Remenyi, Alan R. Kerr, Nigel J. Wilson

The authors evaluated ventricular function after AR or MR in young patients with regurgitation and preoperative signs of ventricular dysfunction.  Results at 18 mos were compared to a normal population.  Persistent LV dysfunction was present in 85% after AR+MR and was more common than after either operation alone.  Preoperative end-systolic volume predicted postop LV dysfunction in pts undergoing isolated MR or AR.

Source: Annals of Thoracic Surgery
Author(s): Hong Meng, Shi-Wei Pan, Sheng-Shou Hu, Kun-Jing Pang, Jian-Feng Hou, Hao Wang

The authors sought to risk stratify pts with secondary TR and then analyze outcomes of different treatment options for TR in conjunction with repair of left-sided valve disease.  Low risk patients did well without TR intervention, intermediate risk patients did well with De Vega annuloplasty, and high risk patients fitted with an undersized annuloplasty ring had good outcomes.

Source: Annals of Thoracic Surgery
Author(s): Dale M. Kobrin, Fenton H. McCarthy, Howard C. Herrmann, Saif Anwaruddin, Sidney Kobrin, Wilson Y. Szeto, Joseph E. Bavaria, Peter W. Groeneveld, Nimesh D. Desai

The effects of renal failure on outcomes of AVR were examined using CMS data.  TAVR pts on dialysis, TAVR pts not on dialysis, and surgical AVR pts on dialysis were compared after propensity score matching.  In TAVR patients, dialysis was associated with increased 30 day mortality and survival, and was an independent predictor of worse survival.  TAVR and SAVR patients on dialysis had similar outcomes, although length of hospitalization was shorter among TAVR pts.

Source: Annals of Thoracic Surgery
Author(s): Mark S. Allen, Shanda Blackmon, Francis C. Nichols, Stephen D. Cassivi, K. Robert Shen, Dennis A. Wigle

The authors evaluated a single year of thoracic surgery operations at their institution and compared outcomes based on data in the American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP), which uses a sampling technique, to the STS General Thoracic Database, a comprehensive data collection system.  Globally, NSQIP underestimated postoperative complications.  When specific procedures were evaluated, the number of errors in NSQIP increased.  The authors concluded that a comprehensive database provide more accurate outcomes information.   

Source: www.anatomyguy.com
Author(s): The Anatomy guy

Check out this amazing free resource on everything you every wanted to know about anatomy. It also has radiology, suturing skills and several other videos and tips. 

 

A fabulous resource 

Source: VUMEDI
Author(s): Dr Michael Mack

Dr. Michael Mack. Patient Background: 49 year old male, Sever Aortic Stenosis with BicuspidAortic Valve, Normal LV with 60 mmhg peak gradient, Valve area- 0.79 cm2, Moderate Aortic Insufficiency, Minimally Invasive Aortic Valve Replacement with a 25 mm Edwards Magna Tissue Valve.

Source: New England Journal of Medicine
Author(s): Patrick Meybohm, Berthold Bein, Oana Brosteanu, Jochen Cremer, Matthias Gruenewald, Christian Stoppe, Mark Coburn, Gereon Schaelte, Andreas Böning, Bernd Niemann, Jan Roesner, Frank Kletzin, Ulrich Strouhal, Christian Reyher, Rita Laufenberg-Feldmann, Marion Ferner, Ivo F. Brandes, Martin Bauer, Sebastian N. Stehr, Andreas Kortgen, Maria Wittmann, Georg Baumgarten, Tanja Meyer-Treschan, Peter Kienbaum, Matthias Heringlake, Julika Schön, Michael Sander, Sascha Treskatsch, Thorsten Smul, Ewa Wolwender, Thomas Schilling, Georg Fuernau, Dirk Hasenclever, and Kai Zacharowski for the RIPHeart Study Collaborators

Pts undergoing cardiac surgery requiring CPB were randomized to remote ischemic preconditioning of the upper extremity or sham intervention.  The end point was combined death, MI, stroke, and acute renal failure during hospitalization, and secondary endpoints were the occurrence of any such event within 90 days.  Outcomes were similar between the groups, with no treatment effects evident on multiple sub-analyses.

Source: New England Journal of Medicine
Author(s): Derek J. Hausenloy, Luciano Candilio, Richard Evans, Cono Ariti, David P. Jenkins, Shyam Kolvekar, Rosemary Knight, Gudrun Kunst, Christopher Laing, Jennifer Nicholas, John Pepper, Steven Robertson, Maria Xenou, Tim Clayton, and Derek M. Yellon for the ERICCA Trial Investigators

Pts undergoing CABG on-pump were randomized to remote preconditioning (upper arm ischemia) or sham intervention prior to surgical incision.  The primary end point was a combination of cardiovascular death, stroke, MI, and revascularization.  At 1 year there was no difference between the groups in the incidence of the end point, and other important clinical outcomes were also similar.

Source: New England Journal of Medicine
Author(s): Raj R. Makkar, Gregory Fontana, Hasan Jilaihawi, Tarun Chakravarty, Klaus F. Kofoed, Ole de Backer, Federico M. Asch, Carlos E. Ruiz, Niels T. Olsen, Alfredo Trento, John Friedman, Daniel Berman, Wen Cheng, Mohammad Kashif, Vladimir Jelnin, Chad A. Kliger, Hongfei Guo, Augusto D. Pichard, Neil J. Weissman, Samir Kapadia, Eric Manasse, Deepak L. Bhatt, Martin B. Leon, and Lars Søndergaard

Patients entered into a clinical trial of TAVR and patients in two registries were evaluated for possible subclinical leaflet thrombosis in their bioprosthetic valves.  40% of the patients in the TAVR trial and 13% of registry patients were found to have such thrombosis.  The risk was lower in patients anticoagulated with warfarin.  Therpeutic anticoagulation for thrombosis resulted in a high rate of resolution.The risk of TIA and stroke was somewhat increased in patients with thrombosis.

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