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Journal and News Scan

Source: Eur J Cardiothorac Surg
Author(s): Christian D. Etz, Ernst Weigang, Marc Hartert, Lars Lonn, Carlos A. Mestres, Roberto Di Bartolomeo, Jean E. Bachet, Thierry P. Carrel, Martin Grabenwöger, Marc A.A.M. Schepens, and Martin Czerny

The paper reviews the anatomy of spinal cord perfusion, strategies to shorten the intraoperative duration of ischemia of the spinal cord, to increase its ischemic tolerance, to detect ischemia and to improve its perfusion.

Source: Eur J Cardiothorac Surg
Author(s): Philipp Kiefer, Jörg Seeburger, Thilo Noack, Thomas Schröter, Axel Linke, Gerhard Schuler, Martin Haensig, Marcel Vollroth, Friedrich-Wilhelm Mohr, and David Michael Holzhey

The procedure of transcatheter aortic valve implantation (TAVI) was analyzed in 2287 patients. About 11% needed surgical interventions, about 2% were converted to full sternotomy and about 1% required use of the heart lung machine. The authors advocate the presence of a cardiac surgeon at each TAVI and building experienced teams within specialized centres.

Source: Eur J Cardiothorac Surg
Author(s): David P. Taggart, Douglas G. Altman, Alastair M. Gray, Belinda Lees, Fiona Nugara, Ly-Mee Yu, and Marcus Flather on behalf of the ART Investigators

This post hoc analysis of the Arterial Revascularization Trial (ART) on 3102 patients compares intraoperative parameters and 1-year outcome for on-pump and off-pump surgery. Both techniques show excellent results with differences only in a small number of secondary endpoints.
 

Source: Journal of Thoracic Oncology
Author(s): Kwon, Woocheol; Howard, Brandon A.; Herndon, James E.; Patz, Edward F.

In this retrospective review of 336 patients treated surgically for early stage NSCLC, the prognostic value of PET SUV was evaluated.  Risks of recurrence and death increased steadily as SUV increased. 

Source: Journal of Thoracic Oncology
Author(s): Bade, Brett C.; Thomas, D. David; Scott, JoAnn B.; Silvestri, Gerard A.

This interesting article summarizes the potential benefits of exercise in patients with lung cancer, including improved exercise capacity and quality of life, and reduced postoperative complications and length of postoperative stay.  This modality is safe, and is likely underutilized in this patient population.

Source: JAMA Surgery
Author(s): Anne O. Lidor; Kimberley E. Steele; Miloslawa Stem; Richard M. Fleming; Michael A. Schweitzer; Michael R. Marohn

This prospective observational study followed 111 patients for 3 years after laparoscopic repair of a type III paraesophageal hernia.  QOL improved at all postoperative time intervals from 28.5 preop to about 10.  The radiographic recurrence rate was 27% at 1 year.  Hernias involving most of the stomach were more likely to recur than smaller hernias.

Source: Lancet Oncology
Author(s): Joe Y Chang, Suresh Senan, Marinus A Paul, Reza J Mehran, Alexander V Louie, Peter Balter, Harry J M Groen, Stephen E McRae, Joachim Widder, Lei Feng, Ben E E M van den Borne, Mark F Munsell, Coen Hurkmans, Donald A Berry, Erik van Werkhoven, John J Kresl, Anne-Marie Dingemans, Omar Dawood, Cornelis J A Haasbeek, Larry S Carpenter, Katrien De Jaeger, Ritsuko Komaki, Ben J Slotman, Egbert F Smit, Jack A Roth

A pooled analysis of outcomes from two randomized trials involving SBRT or surgery for operable patients with clinical early stage NSCLC was performed. The number of patients was small (58 total) and the follow-up was a median of 35-40 mos.  Overall 3-year survival was better in the SBRT group (95% vs 79%; p=0.037) whereas recurrence free survival did not differ between the groups.  Grade 4 complications or death occurred in 48% of surgical patients (1 mortality) and in none of the SBRT patients.

Source: The Annals of Thoracic Surgery
Author(s): Prashanth Vallabhajosyula, Tyler Wallen, Aaron Pulsipher, Emil Pitkin, Lauren P. Solometo, Shenara Musthaq, Jeanne Fox, Michael Acker, W. Clark Hargrove III

This retrospective review compared outcomes for re-do minimally invasive mitral valve operations vs re-do sternotomy in mitral valve operations. The authors demonstrate a similar MV-repair rate in the two groups but a significantly lower bypass and cross-clamp time in the minimally invasive group. Working within the confines of a retrospective study the authors have produced a very interesting paper.

Source: New England Journal of Medicine
Author(s): Gerard A. Silvestri, Anil Vachani, Duncan Whitney, Michael Elashoff, Kate Porta Smith, J. Scott Ferguson, Ed Parsons, Nandita Mitra, Jerome Brody, Marc E. Lenburg and Avrum Spira for the AEGIS Study Team

Pts with suspected lung cancer underwent sampling of normal-appearingbronchial epithelial cells in the main bronchi, unrelated to the suspected tumor.  Gene expression was analyzed and classified.  Classification for cancer was about 75% accurate. 

Source: Annals of Surgery
Author(s): Roberts, Derek J.; Leigh-Smith, Simon; Faris, Peter D.; Blackmore, Christopher; Ball, Chad G.; Robertson, Helen Lee; Dixon, Elijah; James, Matthew T.; Kirkpatrick, Andrew W.; Kortbeek, John B.; Stelfox, Henry T.

The question in this review was whether patients who experience tension pneumothorax differ in presentation depending on whether they are breathing spontaneously or are on positive pressure ventilation.  Assisted ventilation was more often associated with hypoxia, hypotension, and cardiac arrest.  These adverse clinical signs frequently arose within minutes of initial clinical presentation in the assisted ventilation cohort.

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