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Journal and News Scan
Interesting multi-center RCT that paves the way for potential paradigm shifts in antithrombotic modulation. The abcence of symptomatic pulmonary embolism warrants further investigation...
Although the standard of care in the West for regionally advanced esophageal cancer entails induction therapy, this is routinely not the case in China. This randomized trial involving over 450 randomized participants to induction therapy (vinorelbine, cisplatin, 40 Gy RT) followed by resection vs resection alone. At a median f/u of 53.5 mos, trimodality therapy demonstrated overall (HR 0.74; CI 0.57-0.97) and disease free (HR 0.60; CI 0.45 to 0.80) survival advantages compared to surgery alone. This study may establish a new standard of care for management of resectable regionally advanced esophageal cancer in China.
On July 22, The Annals of Thoracic Surgery published this consensus statement on nomenclature and classification of the congenital bicuspid aortic valve (BAV) and Its aortopathy.
This consensus statement divides BAV into 3 types: 1) Cusp-fused type (right-left, right-non and left-non-coronary cusp fusion ); 2) Two-sinus type (latero-lateral and antero-posterior ); and 3) Partial-fusion (forme fruste) type.
BAV-associated aortopathy are categorized into 3 types: 1) Ascending type; 2) Root type; and 3) Extended type.