This randomized trial assigned septic pts to resuscitation with a MAP goal of 80-85 mm Hg or 65-70 mm Hg. There was no difference in mortality at 30 or 90 days. Afib was more common in the high goal pts, and high goal pts with chronic hypertension required less renal replacement therapy.
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Critical Care
March 15, 2014
This meta-analysis evaluated the 4 new oral anticoagulants and compared their efficacy and side-effects to those of warfarin using results from randomized trials of treatment of afib. Outcomes in nearly 72,000 recipients were evaluated, including stroke, embolic events, mortality, MI, and bleeding. The newer anticoagulants reduced stroke risk by 19