Extracapsular spread of cancer cells is associated with poorer outcome compared to intracapsular limitation in positive lymphnodes in patients with adenocarcinoma of the oesophagus and gastro-oesophageal junction. This finding is not reflected by the current tumour staging system.
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Esophagus - Cancer
May 27, 2014
This metanalysis identified 26 eligible studies that assess the predictive value of PET for survival after induction therapy. Complete metabolic response was associated with a 50% decrease in mortality and in tumor recurrence compared to no response.
May 21, 2014
The PORTICO trial has opened to evaluate the Portico Transcatheter Aortic Valve System. This prospective multicenter trial involving up to 40 sites will randomize pts to Portico vs another TAVR valve in the US.
February 15, 2014
Pts surviving esophagectomy longer than 10 years were queried as to QOL. Alimentary comfort rating was 9 out of 10. 33% experienced diarrhea, dumping, or regurgitation. 15% had aspiration requiring hospital care. Mean weight loss was 26 lbs. Median GI QOL score was 2.9 out of 4.
February 10, 2014
The CROSS trials randomized pts with esophageal cancer or GEJ cancer to surgery vs induction chemoradiotherapy (CRT) followed by surgery. Prior studies reported a significant improvement in survival and freedom from recurrence associated with induction therapy.
December 4, 2013
This video demonstrates the treatment of esophageal squamous cell carcinomas through high intrathoracic circular anastomosis using a thoracoscopic technique.
July 19, 2012
The Novalung Interventional Lung Assist (iLA) device is a membrane ventilator that allows for oxygen and carbon dioxide gas exchange to occur by simple diffusion.
August 2, 2011
Transhiatal esophagectomy (THE) may be used to treat patients with either benign or malignant esophageal disease because the reconstructive result cervical esophagogastric anastomosis yields an excellent functional result with a minimum of gastroesophageal reflux. In practice, the majority of patients who require esophagectomy have malignant disease.
February 15, 2011
James Luketich, MD, interviews Mark Orringer, MD, who discusses the procedure that he helped pioneer: thetranshiatal esophagectomy. He reviews the key steps in the procedure to make this a successful operation.