Declines in US annual lung cancer mortality rates of 5% for men and 4% for women led improvements in overall cancer mortality rates in the latest update from the American Cancer Society. This is likely linked to efforts at decreasing tobacco use, improved screening, and newer systemic therapies.
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Lung - Cancer
January 10, 2020
Benign-appearing lung nodules identified on screening CTs are associated with an increased risk of lung cancer diagnosis 4 to 8 and 8 to 11 years after the scan (RRs 1.9 and 1.6, respectively).
December 18, 2019
Performance of curative surgery for early stage cancer varied considerably among counties in the US, and was related to socioeconomic factors, availability of surgeons, and non-metropolitan status.
November 7, 2019
This brief overview of recently presented improvements in lung cancer therapy highlights the substantial benefits of newer chemotherapy and immunotherapy regimens that are transforming the outlooks of many patients with advanced lung cancer.
October 24, 2019
This multiinstitutional study including advocates of robotic lung resection identified a 1.9% incidence of intraoperative castrophes, most commonly pulmonary arterial bleeding. Patients at risk had lower FEV1%, higher clinical stage, and more frequent preoperative radiation therapy.
October 24, 2019
This analysis of data from the JCOG0201 trial identified factors that place patients at increased risk for recurrence after lobectomy for stage I adenocarcinoma. They include visceral pleural invasion, vascular invasion, or an invasive component measuring >2 cm.
October 21, 2019
Better cardiorespiratory fitness as quantified by treadmill exercise testing was associated with a substantially decreased likelihood of lung cancer in former smokers (77% reduction in very fit) and reduced mortality in smokers who subsequently developed lung cancer (85% reduction in very fit).
September 27, 2019
Interesting to see the long term curative results of this randomized controlled trial.
September 20, 2019
Immune checkpoint inhibitors have revolutionized treatment of non-small cell lung cancer. In this study, breath prophiles were collected from 143 patients and a single biomarker profile was created that detected responses to anti-PD-1 treatment with 89% accuracy.
August 22, 2019
This study of over 25,000 pts from the International Lung Cancer Consortium identified underweight and severly obese patients as having poorer survival than others, whereas a survival advantage was evident among patients who were overweight or mildly obese. Decreased BMI (wt loss) was associated with poorer outcomes across all BMI categories.