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Lung Cancer - Surgery

March 5, 2017
The authors report the use of ECMO in 8 pts who suffered ARDS after pneumonectomy.  Predicted mortality was 80% prior to ECMO institution.  ECMO was weaned in 7 pts and overall hospital survival was 50%.  
October 31, 2016
The authors examined the concordance of clinical and pathological staging using prospectively collected data from the Dutch Lung Surgery Audit, examining patients with clinical stage I disease.  Among 1,555 patients, the concordance of cTNM and pTNM was 60%.  22.6% of patients were upstaged after resection, .  The difference was more evident in patie
September 27, 2016
The success of training techniques including dividing robotic lobectomy into graduated steps, reviewing video peformances of trainees, and coaching through challenging technical maneuvers were tracked during a 5-year experience.
August 28, 2016
The authors tested the hypothesis that induction therapy improves survival in patients undergoing resection for clinical N1 disease using information from the National Cancer Data Base.  10% of over 5,000 pts were treated with induction therapy.  They were 2:1 propensity matched with patients undergoing the traditional surgery first strategy.  Among
August 4, 2016
Using a Taiwanese national database, the authors evaluated long-term survival after VATS vs open lobectomy for lung cancer using propensity matching and multvariate analyses.  Among 5,222 patients, 2,164 (41%) had a VATS approach.  Propensity matching yielded 1848 patients in each group.  5-year survival was similar for the VATS and open groups (68.7
August 2, 2016
This randomized trial evaluated the efficacy of postoperative metoprolol or losartan in preventing atrial fibrillation in patients with elevated N-terminal pro-brain natriuretic peptide who were undergoing lung resection for cancer.  Among candidates, 29% (320) of patients had elevated NT-proBNP and were randomized.  Both metoprolol and losartan redu
June 11, 2016
The authors summarize findings in a single institution retrospective review of patients undergoing pre-discharge VTE screening after pneumonectomy for NSCLC and compare outcomes to an historic series of patients who did not have screening.  Rates of VTE in the screened group were 8.9% at discharge, an additional 3.4% within 30 days postop, and 5.4% &
June 11, 2016
The author describes the growing role of SBRT in lung cancer therapy and the growing role of radiation oncologists in decision-making regarding lung cancer.  The cautionary note is that surgeons need to remain actively involved in staging, patient assessment, and treatment recommendations. Commentary:
June 4, 2016
The authors used data from the NCDB to assess long-term outcomes after SBRT (1,781) or lobectomy (13,562) for clinical stage I NSCLC in patients without important co-morbidities.  Overall survival was significantly better after lobectomy for T1N0 (HR 0.38) and for T2N0 patients (HR 0.38).  Propensity score matched patients (1781 pairs) also had signi
March 27, 2016
The authors provide a comprehensive and exhaustive review of the literature comparing lobectomy to sublobar resection for treatment of early stage NSCLC. The focus of the study was to highlight the methodological differences used and determine if comparisons between studies can be made.

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