Data from the National Lung Screening Trial (NLST) were examined by exploring different size thresholds for classifying CT screening scans as positive. In the NLST, nearly two-thirds of nodules were 7mm in diameter or less. Using a threshold of 5mm, the percentage of missed/delayed diagnosis and the likelihood of avoiding false positive findings we
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Lung - Cancer
November 24, 2014
November 20, 2014
Data from 20 observational studies including nearly 3000 pts were reviewed to assess the prevalence of pre-frailty/frailty and clinical outcomes in older cancer patients. Frailty was identified in 42% and pre-frailty in 43% of patients. Combined frailty was associated with increased all cause mortality (5-yr HR 1.57), postoperative mortality, and p
November 18, 2014
This video demonstrates a uniportal non-intubated VATS lobectomy in an elderly patient with a lower left lobe tumor.
November 16, 2014
This expert technique offers a step-by-step approach to right upper lobectomies through a full thoracoscopic posterior approach.
November 11, 2014
CMS determined that the evidence of benefit for CT screening for lung cancer is sufficient to permit this as an annual benefit for Medicare and Medicaid recipients in the US. The availability of such coverage will be limited, however, by the need to have the screening as part of a comprehensive counseling (smoking cessation, etc) visit with qualifie
November 11, 2014
This study explored financial conflicts of interest (FCOI) among authors of published guidelines and consensus statements and their relationship to endorsement of specific drugs. 93% of recent articles reported FCOI status. Of articles publishing funding sources, 65% reported partial or full industry funding. Endorsement of chemotherapeutic agents
November 11, 2014
Differentiating a primary lung cancer from an intrapulmonary metastasis can be challenging. The authors developed a lineage test using whole genome amplification and next-generation sequencing to identify breakpoints in known primary tumors and known metastases. Independent primary tumors did not share any genomic rearrangements, whereas primary tu
November 10, 2014
Joel Dunning talks with Douglas Wood about key aspects of general thoracic surgery and the importance of specialization for the future of the specialty in a interview recorded at the 2014 EACTS Annual Meeting.
November 5, 2014
The authors examined cost-effectiveness in the National Lung Screening Trial (NLST), examining incremental cost-effectiveness ratio (ICER) and quality-adjusted life years (QALYs) associated with low dose CT screening. The ICER was $52,000 per life-year gained and the $81,000 per QALY gained. These values were very sensitive to variations in the scr
November 5, 2014
The potential benefit of wedge resection vs anatomic resection for stage I and II lung cancer was examined using propensity score matching for pts from the STS Database. Over 3700 pts were matched in each group. Wedge resection was associated with fewer major complications (4.5% vs 9.0%) and lower mortality (1.2% vs 1.9%). Wedge resection reduced