Because of the observation that already debilitated pts who undergo lung resection become even more debilitated afterwards, the authors conducted a randomized trial of endurance and strength training for 20 wks after major lung resection. Training significantly improved peak VO2, DLCO, strength, endurance, and muscle mass compared to controls. Qual
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Lung - Cancer
October 16, 2014
October 15, 2014
Using a data set of over 76,000 women from the Women's Health Initiative Observational Study, the effects of active and passive smoking on cancer were evaluated. Lung cancer incidence was highest among active smokers (HR 13.44) and was also high among prior smokers (HR 4.20). A prolonged exposure (>30 yr) to passive smoking in the household also
October 14, 2014
Lung cancer cases 2000-2013 in the UK Health Improvement Network were evaluated for factors associated with early death (within 90 days of diagnosis) vs later death. Risk factors for early death included male sex, older age, current smoking, social deprivation, and rural location. Those experiencing early death saw their primary care physicians mor
October 1, 2014
Using a single institution database, the authors propensity score matched patients receiving wedge resection, wedge resection plus brachytherapy, or SBRT for early stage NSCLC. Survival was assessed at a median of 35 mos. Overall recurrence was higher for SBRT vs wedge (30% vs 9%), and recurrence-free and disease-free survival were better after wed
September 25, 2014
Costs of lung cancer screening were determined for individuals with a 2% or greater risk of lung cancer over 3 years for 2059 subjects participating in the Pan-Canadian Early Detection of Lung Cancer Study. During the first 18 mos of screening the per-person cost was $453. Surgical therapy cost $33,344 over 2 years compared to costs of treating adv
September 25, 2014
A model for predicting lung cancer in patients with suspicious lung nodules (TREAT) was developed using single institutional data (Vanderbilt), validated using data from another institution, and compared to the Mayo Clinic predictive model. The model accuracy was 87% in the development cohort and 89% in the validation cohort, compared to 80% in the
September 25, 2014
This meta-analysis of 70 studies evaluated the utility of PET in assessing over 8,511 lung nodules, comparing regions in which infectious lung disease is endemic to other regions. Specificity was lower in regions with endemic infectious diseases, 61% vs 77%. Overall, the accuracy of PET was extremely heterogeneous.
September 12, 2014
This multi-institutional phase II trial (80 patients from 17 Canadian institutions) was performed to assess if a hypofractionated accelerated radiotherapy regimen for cytohistological-proven early stage NSCLC (peripherally located T1 to T3 N0 M0) has a good local control rate.
September 8, 2014
This video shows a 3 cm single incision VATS left-lower lobectomy and lymph node dissection for non-small cell carcinoma.
September 5, 2014
Screening for lung cancer with low-dose CT has been shown to save lives, but few people who qualify for screening actually receive it. This study examined the use of the electronic medical record to identify pts at risk due to a smoking history. Prior to initiation, the annualized rate of referral for screening was 16 pts. After initiation the ann