This retrospective review evaluated the relationship of pretreatment vs post-induction therapy stage to survival in patients undergoing surgery for esophageal adenocarcinoma in 2 centers in London. Among 584 pts, 400 underwent induction therapy. Downstaging predicted improved survival (HR 0.43). Downstaging was associated with decreased rates of l
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Cancer
September 25, 2014
September 25, 2014
This meta-analysis of 70 studies evaluated the utility of PET in assessing over 8,511 lung nodules, comparing regions in which infectious lung disease is endemic to other regions. Specificity was lower in regions with endemic infectious diseases, 61% vs 77%. Overall, the accuracy of PET was extremely heterogeneous.
September 16, 2014
This retrospective review of pts undergoing complete resection by extrapleural pneumonectomy 1998-2011 for malignant mesothelioma focused on stage predictors of survival. Surgical mortality was 5%. Overall survival at 5 years was 14%, and median survival was 18 mos. Median survival for N1 or N2 disease was 17 and 13 mos, respectively. Nodal stag
September 16, 2014
This retrospective study evaluated recurrence patterns and management of recurrence after bimodality (chemoradiotherapy) for esophageal cancer in 276 pts. Local relapse alone developed in 23%, and 36% of those patients had salvage esophagectomy. Median survival for those undergoing salvage esophagectomy was 59 mos, whereas pts who were not offered
September 12, 2014
This multi-institutional phase II trial (80 patients from 17 Canadian institutions) was performed to assess if a hypofractionated accelerated radiotherapy regimen for cytohistological-proven early stage NSCLC (peripherally located T1 to T3 N0 M0) has a good local control rate.
September 8, 2014
This video shows a 3 cm single incision VATS left-lower lobectomy and lymph node dissection for non-small cell carcinoma.
September 5, 2014
Screening for lung cancer with low-dose CT has been shown to save lives, but few people who qualify for screening actually receive it. This study examined the use of the electronic medical record to identify pts at risk due to a smoking history. Prior to initiation, the annualized rate of referral for screening was 16 pts. After initiation the ann
September 5, 2014
This single institution study tracked outcomes of a unique lung cancer survivorship program facilitated by a nurse practitioner who was trained in survivorship care. The nurse took over follow-up care of early stage patients who survived disease-free for more than 1 year. 92% of eligible pts received follow-up care by the nurse. The program identi
August 31, 2014
In this retrospective study based on a database of 5390 patients with early-stage esophageal cancer, T1a and T1b lesions were treated by endoscopic (26.5%) or surgical resection (73.5%). For patients undergoing surgery, the incidence of lymph node metastasis was 5.0% for T1a and 16.6% for T1b lesions.
August 20, 2014
This video demonstrates a VATS right upper lobectomy in a patient with previous esophageal and breast cancer.